Luxury vacation homes inIsle of Palms, South Carolina
Our favorites
Discover luxury vacation rentals in Isle of Palms. All curated by people, not algorithms. Every property is hand-selected, but these are the ones that made us say 'wow'.
Charleston's coastal playground
Experience the coastal beauty of Isle of Palms, South Carolina from the comfort of a luxury vacation home. This Charleston-area barrier island combines pristine beaches, family-friendly atmosphere, water sports, and Lowcountry charm. Whether you're enjoying beach activities, exploring Wild Dunes Resort, or visiting nearby Charleston, premium KEY.co Isle of Palms vacation rentals provide the perfect family beach getaway.
Our curated selection of luxury vacation rentals in Isle of Palms offers something for every traveler - from beachfront properties with ocean views to modern homes near golf courses. Each rental home features thoughtful amenities, stylish décor, and the authentic Isle of Palms experience you're seeking. Discover why families love this welcoming destination while enjoying the privacy and comfort of your own vacation home on Isle of Palms' beautiful shores.
Private pool havens
Built for entertaining
Why KEY
We curate exceptional homes and arrange every detail so you can simply arrive and relax.
Homes that raise the bar
Our portfolio is small on purpose. Every home is professionally managed, design-forward, and vetted for comfort and style.
Services to elevate your stay
After booking your home, complete your stay with tailored services. From pre-arrival groceries and private chefs to in-home massages.
A team who obsesses over every detail
From hand-selecting homes to coordinating logistics, our team makes planning seamless. Your only to-do is to arrive and relax.
Escape beyond Isle of Palms
Your wanderlust doesn't have to stop here. Discover what other destinations are calling.
Explore Locations
Wherever you're headed, make it memorable with KEY.